The NPDI collection, which is considered to be one of the most pharmaceutically promising in the world, was constructed with the goal of rapid and easy discovery of medically important compounds. It has a track record of yielding novel bioactive compounds. Some have led to “blockbuster” drugs. The NPDI also has considerable “know-how” regarding the collection’s maintenance, recovery, and follow-up. The collection is specifically comprised of more than 22,000 plant, 35,000 actinomycetous, and 45,000 fungal extracts as well as approximately 20,000 bacterial strains.